Two of the most powerful gangs in Los Angeles, the LA County Sheriff's Department's "Major Crimes" unit and a bank robbery crew known for its escalating heists, finally cross paths when the bank robbers decide to hit the Federal Reserve Bank. Led by officer Nick Flanagan, the officers in Major Crimes who are known for living and working without limits do everything they can inside and outside of the boundaries of the law to catch the thieves. They soon learn though that these thieves are different: They live without fear and feel no guilt about the consequences of their actions.
