Grace and Frankie's husbands are business partners that come out of the closet after many years of a secret affair. Grace and Frankie become housemates, each with very different lifestyles. Their grown children adapt to this new parental situation as their fathers desire to marry. Grace and Frankie look to learn ways to adapt to being single as seniors. Grace and Frankie is a modern day seniors plot that focuses on current social dilemmas using a comic style. Current day issues addressed is the blending of conservative and liberal lifestyles, gay lifestyles, interracial families, senior dating, and woman in business.